Searchable abstracts of presentations at key conferences in endocrinology

ea0094p73 | Metabolism, Obesity and Diabetes | SFEBES2023

Fulminant diabetic ketoacidosis occurring one year after immune checkpoint inhibitor-induced hypothyroidism while on pembrolizumab: a case report

Ramburuth Vivek , Umer Reham , PV Vegesna Ram , V Sagi Satyanarayana , O Oyibo Samson , Z Htun Kyaw

Introduction: Pembrolizumab is an immune checkpoint inhibitor (ICI) used to treat advanced cancers. While improving survival rates, ICIs also cause immune-related adverse events (IRAEs). The endocrine system remains the most vulnerable to IRAEs: thyroid involvement is the commonest while pancreatic involvement is rare, affecting less than 1% of individuals. Risk factors for IRAEs include, personal or family history of autoimmune conditions, presence of another...